Corks N Caps(brew club) meets at the MidTown Tavern on Riverfront once a month, not entirely sure when. I think its Thursdays but not sure what week. My buddy is a member, I'll get some info from him and update ya real soon.
I'm pretty sure there is a homebrew club in Rochester. I used to live in Winona (now St. Paul) but I wasn't into brewing then so my knowledge is limited. A quick google search led me to this link: http://www.razebrewing.com/