I have designed several systems and detailed them in my blog:
Also, my brewery build thread is in my signature line.
To give you a real answer we need to know a couple of things:
1. What is your budget? You don't need all the money up front, but how much do you intend to spend on your brewery?
2. What capabilities do you want need? If you are not sure, we can figure that out later.
3. What type of beers are you planning to brew?
4. Do you have DIY skills and tools?
5. What materials do you want to use, SS, Al, Cu, etc?
6. Single, two, or three tier?
7. Gas or electric?
I am sure we will think of more questions as they come up!!