That was my problem last year. I kept going out of town so I only hit my mites with neem oil twice. It didn't work. This year, I guess I will try to spray them off with a sprayer every day and then neem oil once a week, twice a week, everyday? 3 years now, my hops get to about 5 feet and then they get sucked dry and I get like two ounces of wet hop in October. It has been a real bumber.