There shouldn't be any difference. I have heard the commercial guys will go about 20 generations then pitch new, but they are turning those generations over in a much shorter timeframe than we usually can.
EDIT: By "generations" I mean batches.
Something is always fermenting....
"It's Bahl Hornin'"
Kegged: Sour Saison, Pale Ale, Aggie Ale, Firestone DBA, De Koninck Blonde
Bottled: Belgian Quad (Grand Reserve), Derangement (Belgian Dark Strong)
On Deck: Pliny the Younger