The 10 lbs of just wheat is going to be the biggest difference. The actual taste difference between the Pilsner an the Light DME is going to depend more on what else you add to the beer. If the DME is the main flavor component, you may taste a little difference. If you add a bunch of specialties, and a bunch of hops, I doubt you'll notice much of a taste difference.
Wyzazz is correct, they are made different.
I do what PT Ray does when I make a wheat with extract. I use all wheat DME ro LME. Then I sometimes even steep a 1/2lb of wheat malt.
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I'm not crazy. My mother had me tested.
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