The RO water is much closer to ur profile, but u would go with the 50/50, why? Also how did u get ur sulfate so high? I could not get it close to 350 without having excessive Ca or Mg. unless ur local water is already high.
I did the water profile once to burton on trent for an Chinook IPA. Not good, the beer had a bad aftertaste i assume from the excessive Calcium, but smelled amazing and had great bitterness.