There is certainly some cellular damage, but you may well be able to recover.
It's critical that you make a starter before pitch for a few reasons:
- See if you have any viability (see if the starter is active)
- Rebuild your cell count up to where it should be
- Beers even under the best conditions benefit from proper pitch rates, which normally means making a starter
With that all said, don't give up. I and many others here have had a brain fart and frozen our yeast, and been able to recover and make a great beer after building a proper starter.