Can I ask from where? Just curious.
I live on the opposite side of LA (east of downtown, airport is west of it) so I know the ones over here. There is a cool pub called Golden Road, a small microbrewery called Eagle Rock. Off the top of my head those are the only ones I know.
If you go to SD, there are a lot of cool places, but it is 2 hours south of LA. Worth it for sure, but maybe not possible for your itinerary.
There are many more microbrews/pubs in LA, I just don't know them very well. I'm always meaning to check them out more, and you have given me a good excuse to do that. I have a couple publications with lists, I can check them out and post again maybe.
When is your trip?