What part of town are you staying in?
If you are actually in SF I would stop by Speakeasy Brewery today from 4-9 for firkin fridays. Theres usually 80 plus people for $3 beers, and the brewer give tours.
Magnolia, 21st Amendment, and Thirsty Bear are all good brewpubs.
Russian River is awesome, but its an hour drive out of the city. If you don't want to travel too far, I would drive over to Berkley/Oakland and stop by Beer Revolution, the trappist, and Triple Rock.