I brew outside, on a 20x30 cobblestone patio, I have a fire extinguisher on hand, I dont enjoy a homebrew until after the hotbreak. I should have a firstaid kit by me, but I do have one in the kitchen. I use welding gloves whenever I move hot stuff so I dont burn myself. I usually brew in shorts and a t-shirt, I wear nonslip work shoes (no flip flops on brew day).
MississippiSlim, I would suggest wearing buttless chaps while brewing so your knees dont burn while boiling