I wouldn't boil or even heat melon, it gives a very unpleasant flavor when done, almost kike a cooked cucumber taste. For melons, just wash the outside very well, sanitize it, a knife, and the cutting board and either wash your hands exceptionally well or wear gloves.
Look up the watermelon wheat recipe by dubbeldach (sp?) on here. It is excellent and tried and true. I've done a watermelon beer several times as well as a honeydew beer and one with a melon called a santa claus melon. Only once did I try and heat the fruit and I'll never do it again! It works on other fruit, just not melon. Good luck!