I've never tried 'Burton-level' sulfate concentrations (>600 ppm) in my pale ales, but I've used the 300 ppm sulfate Pale Ale profile included in Bru'n Water dozens of times. Its straight out of ProMash (with minor treaking to get it to balance) and I understand that it may have originally been presented by Randy Mosher. 300 ppm sulfate is not overbearing by any measure when used in a hoppy beer.
I highly recommend brewers experimenting with punching up their Pale Ales try the Pale Ale profile first. If you're brave, try the Burton profile. I think 300 ppm sulfate is enough in a hoppy beer.
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