I'm not a big fan of the Cascade hops, just because I don't like the citrus in my beer, but YMMV.
My LHBS uses Bullion for their IPAs, but if you have those two, I'd do the Nugget as a bittering, and Cascade as aroma or dry hop addition.
If you are not growing your own 6th generation barley and hops, you're not *really* homebrewing.
Fermenting: Real Ale, Extract Lager (with WLP830), India Pale Ale
Drinking: Pale Ale from the keg